Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that individuals with insomnia who take melatonin supplements for over a year face an increased risk of heart failure compared to those who do not use this common sleep aid.
Study Findings
The study shows that people using melatonin long-term were more likely to be diagnosed with heart failure, hospitalized for it, or to die from any cause. These findings were presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans.
Preliminary Research Status
This investigation has yet to be published in a peer-reviewed journal. Researchers emphasize that the study does not prove a direct cause-effect link between melatonin use and heart failure.
“Melatonin supplements may not be as harmless as commonly assumed.”
Safety Concerns and Regulation
The researchers highlighted concerns about the long-term safety of melatonin supplements, suggesting additional studies are necessary to evaluate cardiovascular risks.
They also noted that melatonin is widely available over-the-counter, often used without medical supervision, and is not strictly regulated.
Author's Summary
Extended melatonin use might elevate heart failure risk, signaling a need for cautious consumption and further scientific investigation into its cardiovascular effects.